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Retinoids accelerate cell turnover clearing hyperpigmented cells faster and stimulate collagen synthesis through different pathway than peptides creating additive improvement, though eye area requires gentle approaches using retinaldehyde or low-concentration retinol (0.25-0.5%) rather than stronger prescription tretinoin risking significant irritation in this sensitive region

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daily injections are unnecessary [2]

DSIP has worked best when I paired it with cutting off screens earlier

The investigators informed patients or their surrogates concerning the study orally and written informed consent was given before entry into the study

Slows keratin assembly and cell division in the follicle matrix